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Objective
To determine the relationship between prior obstetrical history and gestational age at delivery in a twin pregnancy.
Design
Retrospective cohort study.
Setting
This is a United States SART CORS database study.
Patients
Patients undergoing IVF in the United States with live delivery of twins.
Interventions
None.
Main outcome measures
The main outcome measures are median gestational age at delivery and rate of preterm delivery (before 37 weeks).
Results
The median gestational age at delivery of IVF-conceived twins was 36.3 [IQR 34.4, 37.6] weeks for nulliparous women, 35.9 [34.0, 37.1] weeks for parous women with a prior preterm birth, and 36.7 [35.1, 37.7] weeks for parous women without a prior preterm birth (p < 0.01 for all comparisons). The rate of preterm delivery was 61% for nulliparous women, 70% for parous women with a prior preterm birth, and 55% for parous women without a prior preterm birth (p value < 0.01 for all comparisons).
Conclusions
Parous women without a history of preterm delivery had lower rates of preterm delivery in a subsequent twin pregnancy compared to nulliparous women. Nulliparous women had lower rates of preterm delivery compared to parous women with a history of a preterm delivery.
Key Words
Article info
Publication history
Accepted:
January 13,
2023
Received in revised form:
December 29,
2022
Received:
July 4,
2022
Publication stage
In Press Accepted ManuscriptFootnotes
Mailing address: LAC+USC Medical Center, 2020 Zonal Avenue, IRD Room 533, Los Angeles, CA 90033,
Identification
Copyright
© 2023 The Author(s). Published by Elsevier Inc. on behalf of American Society for Reproductive Medicine.
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